Elixirs of Poison Resistance are crucial consumables in Diablo 4, enhancing your resistance to poison attacks and accelerating experience gains. 

Elixir is Crafted

To make an Elixir of Poison Resistance, gather ingredients from the loot of your enemies or chests. It depends on the ingredient's strength so even a lesser version can be helpful.

Location of the Elixir

Enemy Drops: Defeated enemies may sometimes drop these elixirs along with other things. Take note that elixirs have different levels and some might be beyond your current limit.

Exploring chests: Throughout the game, there are chests that contain elixirs like poison resistance among others, especially event-related ones.

How to Consume an Elixir

Elixir Activation: Select your Consumable Tab and use it to activate an elixir which boosts poison resistance for 30 minutes.

Emote Wheel Use: By adding this elixir to your Emote Wheel, you can easily consume it when you want especially during battle.

Understanding the Active Elixir Status

After consuming another elixir of poison resistance, previous one's effect will disappear. Only one elixir of poison resistance can be active at a time.

Tactics in Using an Elixir

Choose the Right Moment: For full benefits of the elixir it is essential to activate it in a safe zone.

Facing Poison Threats: When there are enemies or areas that use poison as their main weapon, consume an elixir for better chances of survival.

Farming experience: Gain more levels quickly by using stronger enemies as experience points banks.