This Diablo 4 guide aims to dissect that information, providing insights into the loot drop systems and what players can expect from each endgame boss.

• Gregor
• Von
• Beast in the Ice
• Lord Zir
• Duriel
• Path to the Bosses
• Closing Thoughts

↖ Gregor

• Common Drops: Staff of Lama, Ice Har Bryce, Gloves of the Illuminator.
• Class-Specific: Staff of Lama (All Classes), Butcher Cleaver (Barbarian), Blood Artisans Curios (Necromancer), Word of Aan (Rogue).

↖ Von

• Common Drops: Staff of Endless Rage, Asus Heirloom, Rayment of the Infinite.
• Class-Specific: Mad Wolf's Glee (Druid), Fields of Crimson (Barbarian), Bloodless Scream (Necromancer), Condemnation (Rogue).

↖ Beast in the Ice

• Common Drops: Staff of Llm, Su's Heirloom, Gloves of the Illuminator, The Oculus.
• Class-Specific: Fields of Crimson (Barbarian), Bloodless Scream (Necromancer), Condemnation (Rogue).

↖ Lord Zir

• Common Drops: Staff of Endless Rage, Ice Heart BR, Ren of the Infinite.
• Class-Specific: Madwolf Glee (Druid), Ramaladni's Magnum Opus (Barbarian), Blood Artisans Curios (Necromancer), Grasp of Shadow (Rogue).

↖ Duriel

• Special Drops: Flame Scar (Sorceress), Zur Wrath (Barbarian), Cowl of the Nameless (Rogue), Tempest Roar (Druid), Black River (Necromancer).
• All Classes: Godslayer Crown, Flicker Step, Tials Will, X Fall's Corroded Signant, Soul Brand, Banish Lord's Talisman.
• Note: Duriel offers a high drop chance for Uber Uniques like Doombringer and Darel's Vis.

↖ Path to the Bosses

Gearing up for these bosses involves a tiered approach. Begin with Whispers and Hell Tides to collect the materials for the first set of bosses. Once vanquished, these bosses provide materials for the next set.

For fans of Diablo 1, the process might resemble the Uber Tristram event. Players will need to gather festering eggs from preliminary bosses to access Duriel. Be cautious: failing against Duriel means you'll lose the ingredients used to summon him.

↖ Closing Thoughts

While the chance to target farm powerful uniques is thrilling, there are concerns about the difficulty level. The current state of Uber Lilith sets a precedent for nearly impossible challenges. The hope is that Duriel is challenging but achievable. He must be tough, but not so difficult that he becomes inaccessible to most players.