In Path of Exile, the Vial of Dominance is a valuable item that can be used to obtain Poe Divines and other rare items, such as the SlaveDriver's Hand and the Architect's Hand. The Vial of Dominance can be obtained by killing the end boss in the Ava's Temple, and players can increase their chances of obtaining it by farming the temple and focusing on certain rooms.

• Set up your Atlas
• Focus on the temple rooms
• Kill mobs and open doors
• Target the apex
• Repeat and farm

 

Here's a guide on how to farm the Vial of Dominance in Path of Exile:

 

↖ Set up your Atlas

Players should aim to have Alpha and the temple mods on the Atlas to receive more master missions and incursions per map. This will allow you to reveal more apexes of the temples and increase your chances of finding the Vial of Dominance.

 

↖ Focus on the temple rooms

Players should aim to reveal the Corruption Chamber (Locus of Corruption Level 3) and Doriani's Institute to increase their chances of getting double-corrupted items and gems. These rooms will help players acquire valuable items, making it easier to farm the Vial of Dominance.

 

↖ Kill mobs and open doors

As you progress through the temple, be sure to kill as many monsters as possible to obtain the keys needed to open more doors and reveal more rooms. This will help you connect the temple rooms and increase your chances of obtaining the Vial of Dominance.

 

↖ Target the apex

The apex of the Ava's Temple is where players will find the end boss that drops the Vial of Dominance. Players should always aim to reach the apex and kill the Omni tech to increase their chances of obtaining the Vial of Dominance.

 

↖ Repeat and farm

Once you have completed the temple, repeat the process by running more maps and revealing more apexes of the temple. This will increase your chances of finding the Vial of Dominance and other valuable items.

 

In conclusion, farming the Vial of Dominance in Path of Exile requires patience, dedication, and a bit of luck. By focusing on the temple rooms, killing as many mobs as possible, and targeting the apex, players can increase their chances of obtaining this valuable item and other rare items.