Diablo 4 features a wide variety of unique items, with over 55+ available in the game. Some of these items are specific to individual classes, while others are universal and can be used by any character. However, what you may not know is that certain enemy types in the game can give you increased drop chances for these unique items. In this guide, we will explore all the in-game uniques and the best places to farm them.

• End of Eels' Visage (Ultra Rare)
• Doombringer (Ultra Rare)
• Fist of Fate
• Harley Quinn Crest (Ultra Rare)
• Penitent Greaves
• Raeset Plate
• Temerity
• Butcher's Cleaver
• The Grandfather (Ultra Rare)
• Necromancer unique items
• - Black River
• - Blood Artisan's Kris
• - Bloodless Scream
• - Deathless Visage
• - Grieves of the Empty Tomb
• - Rays of Plate
• - Tempestuary
• - Butcher's Cleaver
• - The Grandfather
• Druid unique items
• - Great Step of the Clone
• - Entity of Fury
• - Mad Wolf's Glee
• - Storm's Companion
• - Tempest of Raw
• Sorcerer unique items
• - Ashio's Khanjar
• - Condemnation
• - Nameless
• - Eyes in the Dark
• - Grasp of the Shadow
• - Sky Hunter
• - Waxing Duos

 

Before we dive into the details, it's worth noting that jewelry items like rings and amulets currently do not have any increased drop chances from specific enemy types. Keep this in mind as you progress through the game. Now, let's start with the universal uniques, which are items that can drop and work on all character classes. This includes the six ultra-rare Uber uniques, which also have increased drop chances from specific enemies.

 

↖ End of Eels' Visage (Ultra Rare)

World Tier 4 only, drops from enemies of monster level 85+.

Increased drop chances from Cortis and Cannibals.

• Recommended dungeons for Cortis enemies: Kong Clay, Serpent's Lair, Shadowed Plunge.
• Recommended dungeons for Cannibal enemies: Gulron Slums, Earthen Wound, Carrow Marsh.

 

↖ Doombringer (Ultra Rare)

World Tier 4 only, drops from enemies of monster level 85+.

Increased drop chances from Snakes, Skeletons, and Beasts.

• Recommended dungeons for Skeleton enemies: Zenith, Core Dragon Barracks, Demon's Wake.
• Recommended dungeons for Snake enemies: Serpent's Lair, Witchwater, Shadowed Plunge.

 

↖ Fist of Fate

Increased drop chance from Spider enemies.

Recommended dungeons: Blind Burrows, Golden Canals, Whispering Pines, Champion's Demise.

 

↖ Harley Quinn Crest (Ultra Rare)

World Tier 4 only, drops from enemies of monster level 85+.

Increased drop chances from Cortis and Cannibals.

• Recommended dungeons for Cortis enemies: Conclave, Serpent's Lair, Shadowed Plunge.
• Recommended dungeons for Cannibal enemies: Gulron Slums, Earthen Wound, Carrow Marsh.

 

↖ Penitent Greaves

Increased drop chance from Drowned enemies.

Recommended dungeons: Haunted Refuge, Dead Man's Dredge, Putrid Aquifier, Vault of the Forsaken.

 

↖ Raeset Plate

Increased drop chances from Beasts and Spiders.

• Recommended Beast dungeons: Blind Burrows, Alderwood, Molded Orders Cave, Haunted Refuge.
• Recommended Spider dungeons: Blind Burrows, Golden Canals, Whispering Pines, Champion's Demise.

 

↖ Temerity

Increased drop chances from Drowned enemies.

Recommended dungeons: Haunted Refuge, Dead Man's Dredge, Putrid Aquifier, Vault of the Forsaken.

 

↖ Butcher's Cleaver

Increased drop chances from Fallen enemies, with additional drop chances from Goldman and Cannibals.

• Recommended Fallen dungeons: Ancient's Lament, Demon's Wake, Conclave.
• Recommended Goldman dungeons: Champion's Demise, Mercy's Reach, Shifter Ruins, Halfthrust Demise.
• Recommended Cannibal dungeons: Gulron Slums, Earthen Wound, Carrow Marsh.

 

↖ The Grandfather (Ultra Rare)

World Tier 4 only, drops from enemies of monster level 85+.

Increased drop chances from Vampires and Spiders.

• Recommended Vampire dungeons: Zenith, Core Dragon Barracks, Heathen's Keep.
• Recommended Spider dungeons: Blind Burrows, Golden Canals, Whispering Pines, Champion's Demise.

After Patch 1.0.4, all unique items, including the six Uber Uniques, can drop from hard-tied chests. So take advantage of this change and keep an eye out for those chests.

 

↖ Necromancer unique items

 

↖ - Black River

Increased drop chance from Drowned enemies.

Recommended dungeons: Haunted Refuge, Dead Man's Dredge, Putrid Aquifier, Vault of the Forsaken.

 

↖ - Blood Artisan's Kris

Increased drop chances from Beasts and Spiders.

• Recommended Beast dungeons: Blind Burrows, Alderwood, Molded Orders Cave, Haunted Refuge.
• Recommended Spider dungeons: Blind Burrows, Golden Canals, Whispering Pines, Champion's Demise.

 

↖ - Bloodless Scream

No specific increased drop chances from enemy types.

 

↖ - Deathless Visage

Increased drop chances from Cortis and Cannibals.

• Recommended Cortis dungeons: Conclave, Serpent's Lair, Shadowed Plunge.
• Recommended Cannibal dungeons: Gulron Slums, Earthen Wound, Carrow Marsh.

 

↖ - Grieves of the Empty Tomb

Increased drop chances from Drowned enemies.

Recommended dungeons: Haunted Refuge, Dead Man's Dredge, Putrid Aquifier, Vault of the Forsaken.

 

↖ - Rays of Plate

Increased drop chances from Beasts and Spiders.

• Recommended Beast dungeons: Blind Burrows, Alderwood, Molded Orders Cave, Haunted Refuge.
• Recommended Spider dungeons: Blind Burrows, Golden Canals, Whispering Pines, Champion's Demise.

 

↖ - Tempestuary

Increased drop chances from Drowned enemies.

Recommended dungeons: Haunted Refuge, Dead Man's Dredge, Putrid Aquifier, Vault of the Forsaken.

 

↖ - Butcher's Cleaver

Increased drop chances from Fallen enemies, with additional drop chances from Goldman and Cannibals.

• Recommended Fallen dungeons: Ancient's Lament, Demon's Wake, Conclave.
• Recommended Goldman dungeons: Champion's Demise, Mercy's Reach, Shifter Ruins, Halfthrust Demise.
• Recommended Cannibal dungeons: Gulron Slums, Earthen Wound, Carrow Marsh.

 

↖ - The Grandfather

Increased drop chances from Vampires and Spiders.

• Recommended Vampire dungeons: Zenith, Core Dragon Barracks, Heathen's Keep.
• Recommended Spider dungeons: Blind Burrows, Golden Canals, Whispering Pines, Champion's Demise.

 

↖ Druid unique items

 

↖ - Great Step of the Clone

Increased drop chances from Fallen enemies and Goldman enemies.

• Recommended Fallen dungeons: Ancient's Lament, Demon's Wake, Conclave.
• Recommended Goldman dungeons: Champion's Demise, Mercy's Reach, Shifter Ruins, Halfthrust Demise.

 

↖ - Entity of Fury

Increased drop chances from Beasts and Spiders.

• Recommended Beast dungeons: Blind Burrows, Alderwood, Molded Orders Cave, Haunted Refuge.
• Recommended Spider dungeons: Blind Burrows, Golden Canals, Whispering Pines, Champion's Demise.

 

↖ - Mad Wolf's Glee

Increased drop chancesfrom Beasts and Spiders.

• Recommended Beast dungeons: Blind Burrows, Alderwood, Molded Orders Cave, Haunted Refuge.
• Recommended Spider dungeons: Blind Burrows, Golden Canals, Whispering Pines, Champion's Demise.

 

↖ - Storm's Companion

Increased drop chances from Drowned enemy types.

Recommended dungeons: Haunted Refuge, Dead Man's Dredge, Putrid Aquifier, Vault of the Forsaken.

 

↖ - Tempest of Raw

Increased drop chances from Cortis and Cannibals.

• Recommended Cortis dungeons: Conclave, Serpent's Lair, Shadowed Plunge.
• Recommended Cannibal dungeons: Gulron Slums, Earthen Wound, Carrow Marsh.

 

↖ Sorcerer unique items

 

↖ - Ashio's Khanjar

Increased drop chances from Bandits and Cultists.

• Recommended Bandit dungeons: Molded Orders Cave, Roffin Wilds, Moogan's Works.
• Recommended Cultist dungeons: Conclave, Serpent's Lair, Shadowed Plunge.

 

↖ - Condemnation

Increased drop chances from Bandits and Cultists.

• Recommended Bandit dungeons: Molded Orders Cave, Roffin Wilds, Moogan's Works.
• Recommended Cultist dungeons: Conclave, Serpent's Lair, Shadowed Plunge.

 

↖ - Nameless

Increased drop chances from Cannibals and Cortis.

• Recommended Cannibal dungeons: Gulron Slums, Earthen Wound, Carrow Marsh.
• Recommended Cortis dungeons: Conclave, Serpent's Lair, Shadowed Plunge.

 

↖ - Eyes in the Dark

Increased drop chances from Drowned enemy types.

Recommended dungeons: Haunted Refuge, Dead Man's Dredge, Putrid Aquifier, Vault of the Forsaken.

 

↖ - Grasp of the Shadow

Increased drop chances from Spider enemies.

Recommended dungeons: Blind Burrows, Golden Canals, Whispering Pines, Champion's Demise.

 

↖ - Sky Hunter

Increased drop chances from Ghosts and Vampires.

• Recommended Ghost dungeons: Earthen Wilds, Onyx Hold, Sunken Ruins, Lost Archives.
• Recommended Vampire dungeons: Zenith, Core Dragon Barracks, Heathen's Keep.

 

↖ - Waxing Duos

Increased drop chances from Fallen and Goldman enemy types.

• Recommended Fallen dungeons: Ancient's Lament, Demon's Wake, Conclave.
• Recommended Goldman dungeons: Champion's Demise, Mercy's Reach, Shifter Ruins, Halfthrust Demise.

 

These are all the end-game uniques in Diablo 4 and the recommended dungeons where you can farm for them. Keep in mind that the drop chances for these items are not guaranteed, and it may take some time and effort to obtain them.